Adverse drug events in people with multimorbidity, polypharmacy and frailty

As they get older, many people develop multiple long-term conditions that affect their health. People with multiple conditions often take multiple medicines.  Medicines help us manage our conditions but they may also cause harm.  Some medicines that we take for different types of conditions have shared harms and may interact with the conditions that a person has. This may increase the risks and harms of medicines. This project will explore how medicines contribute to risk of falls and kidney damage, and how their risk varies depending on other conditions or prescriptions that a person has.  

The aim is to examine the risk of harms associated with different medicines, and whether the risk of medicines varies in people:
-     With multiple health conditions
-     On combinations of medicines that may cause the same harm
-     Taking multiple medicines even if not known to be associated with a specific harm